Renal involvement in 35% of mixed cryoglobulinemia vasculitis Associated with : • Absence of skin lesions • Absence of peripheral neuropathy • Type II cryoglobulinemia • Combined decr of C3 and C4 levels Characteristics at presentation • Hematuria - 97% • Mean proteinuria - 3.5 g/day (%) • > 3g / day - 49% • Hypertension (%) - 85% • Mean eGFR - 39.5 mL/min • <60 mL/min/1.73m2 - 82% • Dialysis (%) - 5% Factors associated with ESRD at last follow-up • eGFR ml/min/1.73 m2 at diagnosis • Dialysis at diagnosis • Extracapillary proliferation • Tendency for nephrotic range proteinuria Dr. Benjamin Terrier @ https://twitter.com/TerrierBen #Renal #Involvement #Cryoglobulinemia #Vasculitis #Management #Rheumatology #Cryoglobulinemic #Nephrology
