12 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... cytopenias (usually anemia ... transformation to acute leukemia ... #treatment #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
: ALL, CML, AML, ... involvement CML ... - infiltrates (anemia ... CLL -> Invade Skin ... #Hematology #Oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... Headaches • Pale skin ... virus (EBV) • Leukemia ... #oncology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
• Most common leukemia ... 5) Symptoms of anemia ... marrow failure with anemia ... #oncology #hematology ... hemeonc #diagnosis #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... Hepatomegaly • Skin ... • Neutropenia, anemia ... diagnosis #workup #oncology ... #hematology
Algorithm for the Treatment of Uremic Pruritus
Nonpharmacologic Treatments:
 • Daily topical emollient
 • Avoidance of extremes
Evidence-Based Off-Label Pharmacologic ... nalfurafine 2.5 mcg ... Pruritus #uremia ... Algorithm #Treatment #management ... #nephrology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
autoantibodies (pernicious anemia ... Worsening macrocytic anemia ... wt loss • If anemia ... - CBC, PBS - anemia ... diagnosis e.g. leukemia
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... • Aplastic Anemia ... Megaloblastic Anemia ... Myelophthisic Anemia ... #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Management of Pruritus in Patients with Chronic Kidney Disease
Pruritus with no primary lesions - differential diagnosis:
pruritus • Hematologic ... Iron deficiency anemia ... • Malignancy (leukemia ... #Uremia #Management ... #Nephrology #CKD