13 results
Map of proliferative blood disorders. 

By Ariella Coler-Reilly @ariellastudies

#Algorithm #classification #proliferative #blood #disorders #leukemia #hematology #oncology
ariellastudies #Algorithm ... #classification ... disorders #leukemia #hematology ... #oncology #diagnosis ... #CML #CLL #AML
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... involvement CML ... ↓ LAP Score • CML ... lymphadenopathy CML ... thrombocytosis) CML
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Acute • Myloid (AML ... Pelger-Huet, Macrocytic anemia ... • Lymphoid (CLL ... CD23, o CML ... #Disorders #hematology
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... a decrease in all ... than 150,000 per mcL ... than 4000 per ml ... than 1800 per ml
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
/dL or CC < 40 ml ... /min A - Anemia ... M spike: • CML ... diseases, CML, ... #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... • Neutropenia, anemia ... microglobulin Treatment ... Transform to DLBCL, PML ... #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
cell count (anemia ... transformation to AML ... Myelogenous Leukemia (CML ... progression to AML ... #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
translocation • Types: Classification ... Malignancies (eg CML ... , ALL) • Solid ... NonHodgkins #comparison #oncology ... #differential #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... Ferritin >1000 ng/ml ... sIL-2R >2400 Ul/ml ... B-LNH), solid cancers ... Unknown cause Treatment
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Treatment ... #hematology #oncology