9 results
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
) Cancer-treatment ... inducers (↑) and inhibitors ... P-glycoprotein is ... #Chemotherapy #Oncology ... #Hematology #Interactions
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
thrombosis in cancer ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology ... #Oncology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from germinal center ... classical HL (MCHL ... Treatment • Early ... classification #hematology ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hodgkin, T-cell lymphoma ... , B-cell lymphoma ... B-LNH), solid cancers ... Unknown cause Treatment ... Anti-IFN-y and JAK inhibitors
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... incompetent • CLL is ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• 75% of ALL is ... count ↑ PLT • ↑ PBS ... organs When Cancer ... #Leukemia #Hematology ... #Oncology #Diagnosis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
(malignancy), lymphoma ... , breast CA - Hematologic ... cancer such as ... Treatment: - Systemic ... #oncology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
pathergy test (this is ... Ischemia, Leukemia, Lymphoma ... Arthritis, AS Treatment ... factor CTNF)-a inhibitors ... monoclonal TNF-aIpha inhibitor
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelogenous Leukemia (CML ... factor (GCSF) treatments ... methyltransferase inhibitors ... Syndromes #diagnosis #hematology ... #oncology