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diagnosis hematology nephrology neurology rheumatology acid acidbase ammonia anemia apml base bloodgas causes classification differentiation disorders encephalopathy erythematosus gas gitelman
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
ABG And BMP Normal ... ) = {Na - (Cl + ... D D-lactate (short ... bowel syndrome, ... restrictive lung disease
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... extramedullary disease ... Philadelphia - BCR-ABL ... • Tumor lysis syndrome ... Leukemia #Hematology #Oncology
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
decompensated liver disease ... , AML - Large ... rare): - Reye syndrome ... deficiency #Ammonia #Pathophysiology ... Hyperammonemia #Differential
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Evans • ITP • Cl-NH ... Sneddon-Wilkinson disease ... Hematology #Monoclonal #Differential ... #Diagnosis #Oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (ACLE ... permanent alopecia Differential ... Shrinking lung syndrome ... • Malar rash - spares ... La, anti-Jo-1, SCL
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Pinpoint-sized red spots ... Myelogenous Leukemia (CML ... Myeloproliferative Disease ... blood count with differential ... diagnosis #hematology #oncology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Pathophysiology ... : • Anti-GAD Ab ... (>1000u/ml) - ... SPS #Diagnosis #Management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Shock, Autoimmune disease ... Etiology: • Pathophysiology ... Anterior circulation: MCA ... Reversible course Differential ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
classical HL (MCHL ... Immunohistochemical studies (to differentiate ... number of sites of disease ... classification #hematology #oncology ... #management
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