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hematology stratification infant pediatrics stepbystep syndrome antibiotics disease febrile hemophagocytic lp lymphohistiocytosis oncology evaluation hemeonc activation admission adult aosd apml
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... Procalcitonin <0.5 ng/mL ... CRP < 20 mg/L #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... sIL-2R >2400 Ul/ml ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
following: • Fever ... Ferritin >500 ng/mL ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Validation of the Step-By-Step Approach to Febrile Infants #Diagnosis #Management #Pediatrics #Peds #Febrile #Infant #StepByStep #Algorithm #LP
Febrile Infants #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile ... #Antibiotics #Risk ... Stratification #Fever
Step by Step Algorithmic Approach to Pediatric Fever Age < 21 days old (or 28 days for
Step by Step Algorithmic ... Procalcitonin >= 0.5 ng/mL ... #Pediatrics #Peds ... #Diagnosis #Management ... #Infant #Fever
Pediatric UTI Algorithm (2-24 months of age) Risk stratify with UTI Calc: - Age months
Pediatric UTI Algorithm ... months of age) Risk ... - No other fever ... #Diagnosis #Management ... UrinaryTractInfection #Peds
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
5000 to 10,000 ng/mL ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Evaluation and Management of Pediatric Fever #Diagnosis #Management #EM #Peds #Fever #Workup #Evaluation #Discharge #Admission #Algorithm
of Pediatric Fever ... #Diagnosis #Management ... #EM #Peds #Fever ... Discharge #Admission #Algorithm ... #Ddxof
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
and Management ... Avoid meds that ... ↑ bleeding risk ... #Management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... search for and treatment ... Fever b. ... Treatment Approach ... #Management #Hematology
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