12 results
Map of proliferative blood disorders. 

By Ariella Coler-Reilly @ariellastudies

#Algorithm #classification #proliferative #blood #disorders #leukemia #hematology #oncology
ariellastudies #Algorithm ... #classification ... disorders #leukemia #hematology ... #oncology #diagnosis ... #CML #CLL #AML
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Algorithm Acute ... CD13, CD33, CD34, HLA-DR ... CD23, o CML ... Blood #Disorders #hematology ... #Algorithm
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... Ferritin >1000 ng/ml ... sIL-2R >2400 Ul/ml ... Unknown cause Treatment ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
following: • Fever ... Ferritin >500 ng/mL ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
hypersensitivity syndromes • HLH ... 5000 to 10,000 ng/mL ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... an infant with fever ... Procalcitonin <0.5 ng/mL ... CRP < 20 mg/L #Diagnosis ... Management #Pediatrics #Peds
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... treatment of Hereditary ... including liver and hematologic ... SF of >1,000 μg/mL ... #hepatology #gastroenterology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
- Pel-Ebstein fever ... translocation • Types: Classification ... Differential Diagnosis ... Malignancies (eg CML ... #differential #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... -95% of cases) Classification ... Hodgkin Lymphoma Treatment ... #classification ... #hematology #oncology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Splenomegaly Diagnosis ... PV, MDS, CML) Treatment ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... #hematology