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management pediatrics rheumatology differential febrile stepbystep antibiotics disease hemeonc hemophagocytic hlh lp lymphohistiocytosis oncology risk stratification activation apml calcium cancer
Causes of Sudden Unexpected Death in Infancy (SUDI) - Differential Diagnosis Algorithm Congenital Anomaly / Disorder: •
Algorithm Congenital ... Neurologic Anomaly • Pulmonary ... Death Syndrome ... #Diagnosis #Algorithm ... #Causes #Peds #
Step by Step Algorithmic Approach to Pediatric Fever Age < 21 days old (or 28 days for
Step by Step Algorithmic ... Procalcitonin >= 0.5 ng/mL ... #Pediatrics #Peds ... #Diagnosis #Management ... #Infant #Fever
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... with fever without ... Procalcitonin <0.5 ng/mL ... CRP < 20 mg/L #Diagnosis ... Management #Pediatrics #Peds
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
Erythematous Rashes - THE ALGORITHMIC ... (SSS) in infants ... and toxic shock syndrome ... #Diagnosis #Dermatology ... Erythematous #Rash #Algorithm
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
The Febrile Infant ... empiric antibiotic treatment ... 92.0% and 46.9% #Diagnosis ... Management #Pediatrics #Peds ... Stratification #Fever
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... frequently affects infants ... following: • Fever ... Ferritin >500 ng/mL ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
- Nonremitting fever ... 5000 to 10,000 ng/mL ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... Imaging: CXR- pulmonary ... #management #hematology
Evaluation of suspected incomplete Kawasaki Disease 1. AHA consensus recommendations 2. Infants ≤6 months old on day ≥7
Infants ≤6 months ... old on day ≥7 of fever ... echo is positive, treatment ... within 10 d of fever ... #Diagnosis #Peds
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... Coronary arteries - Fever ... Vasculitis: • Fevers ... testes -> pain, infarct ... #rheumatology #
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