11 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
A subset of hemophagocytic ... Clinical Presentation ... 5000 to 10,000 ng/mL ... #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... Ferritin >500 ng/mL ... #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... accumulation of clinical ... Assessment • Clinical ... #management #treatment ... #summary #rheumatology
Posterolateral Corner (PLC) Injury - Posterolateral Drawer Test
Injury to the posterolateral corner (PLC) is difficult to
is difficult to diagnose ... This video shows ... ligament injury (PCL ... Test #Positive #Clinical ... Knee #Posterior #msk
â–ş
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... (Clinical Dx). ... ) Differential Diagnosis ... #diagnosis #management ... signs #symptoms #rheumatology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... renal failure Clinical ... Pulmonary: dyspnea ... anterior/posterior MSK ... #Management #Signs
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... , INC risk PE, Pulmonary ... phenomenon (16%) MSK ... #Rheumatology # ... Diagnosis #Management
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
symptoms • Rheumatologic ... has five major clinical ... fungal stain of clinical ... MC: CNS CSF: • ... #Management #Infections
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Hemophagocytic Lymphohistiocytosis ... recognition and management ... Clinical Presentation ... #HLH #Hemophagocytic ... #Management #Hematology
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... Relapsing-remitting course +++ Clinical ... filling +++ (risk of pulmonary ... #diagnosis #management ... timeline #treatment #rheumatology