6 results
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• MM • WM • MGUS ... • MGCSMGRS ... Dermato-neuro syndrome) MGRS ... WAIHA • CAD • PCH ... Paraproteinemias #Hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Donath-Landsteiner Antibodies[PCH ... - Mycoplasma, EBV ... significance (MGUS ... Hemoglobinuria (PCH ... hemolytic #anemia #hematology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
biliary cirrhosis (PBC ... Celiac disease Anti-GBM ... diagnosis #table #rheumatology
Scaphoid Fractures
The scaphoid is the most commonly fractured carpal bone. Remember, if a fracture is suspected
Thumb spica • Ortho ... follow-up with PCP ... MH/CCF/CWRU EM
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Gammopathy Include: • MGUS ... acute HIV, HBV, EBV ... lung cancers, HCC ... gastric tumors • Hematology ... differential #diagnosis #hematology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... • ANA < 20 % IBM ... Other Diseases: • PBC ... Myositis #Myopathy #rheumatology