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monoclonal oncology gammopathy agglutinin aplastic arthritis complications differential disease gammopathies gout gouty hemolytic impingement lavallee lavallée lesion management morel multiplemyeloma
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• MM • WM • MGUS ... • MGCS • MGRS ... Dermato-neuro syndrome) MGRS ... due to cold IgG ... Paraproteinemias #Hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Significance (MGUS ... Prevalence M > F MGUS ... IgM MGUS: • Serum ... constitutional symptoms ... #Significance #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... of anemia include ... anemia • Cold ... significance (MGUS ... #hematology #diagnosis
Posterior Ankle Impingement (Os Trigonum) Syndrome - MSK Radiology Imaging Findings: • Os trigonum which has marrow
Radiology Imaging ... flexion but no symptoms ... #mri #clinical ... #Radiology #diagnosis ... #msk
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
40 ml/min A - Anemia ... focal lesions on MRI ... #Gammopathies #MGUS ... #diagnosis #hematology
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gouty Arthritis) - MSK ... Radiology Imaging ... #clinical #Radiology ... #diagnosis #msk ... #rheumatology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS) Fracture, Osteoporosis - Increased osteoclast activity and bone resorption
Significance (MGUS ... rituximab (in clinical ... high-risk situations #MGUS ... Complications #diagnosis ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... Anticonvulsants - Gold ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management
Morel-Lavallée Lesion - MSK Radiology Imaging Findings: • Large, smoothly marginated, well-circumscribed mass along the medial myofascial
Radiology Imaging ... Abscess: Absence of symptoms ... #mri #clinical ... #Radiology #diagnosis ... #msk
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