MGUS mgrs clinical msk diagnosis symptoms rheumatology mri lupus radiology cold gammopathy

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Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
1. Cold Agglutinins (CAD)
2. Donath-Landsteiner

Viral Infection Clinical ... IgM monoclonal gammopathy ... significance (MGUS ... hemolytic #anemia #hematology ... #diagnosis

Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
- Increased osteoclast activity and bone resorption

Significance (MGUS ... treatment of infective symptoms ... rituximab (in clinical ... high-risk situations #MGUS ... Complications #diagnosis

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