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diagnosis sle algorithm comparison complications dermatology differential diffuse druginduced focal hairloss management manifestations mucocutaneous rheumatology signs symptoms
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Vitamin A Excess - Drugs ... • Hyperthyroid drugs ... Disease • Discoid ... lupus erythematosus ... Diagnosis #Algorithm #causes
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
areas -> Scaring alopecia ... hair follicles -> causes ... follicular plugging -> Discoid ... mechanism) -> Alopecia ... Manifestations #pathophysiology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... cases, drug-dependent ... Discontinuation of causal ... Positive in 60-80% of cases ... sle #comparison #table
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