9 results
ANTIBIOTIC SUSCEPTIBILITIES IN INTENSIVE CARE

Antibiotic spectra made simple(r). Version 2, now updated with new bugs &
with new bugs & drugs ... #Antibiotics #Classes ... Susceptibilities #ICU ... CriticalCare #Overview #Pharmacology
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Delirium (PAD) in the ICU ... Addressing the ICU ... assessment of the ICU ... A dissociative drug ... non-OTC prolonging agent
Delirium in the ICU

Defining delirium
Types of delirium
Consequences of delirium
Reversible causes of delirium
Drug-induced delirium
Non-pharmacologic management of delirium
Pharmacologic
Delirium in the ICU ... delirium Reversible causes ... of delirium Drug-induced ... theABofPharmaC #ICU ... #Delirium #pharmacology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
areas -> Scaring alopecia ... hair follicles -> causes ... butterfly) Rash • ICx ... mechanism) -> Alopecia ... Manifestations #pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
cytotoxic reaction to drug ... Systemic effect -> Nausea ... , weight gain, alopecia ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... immune deficiency, Drugs ... , Unknown cause ... 100 mg/m2) : in case ... of emergency, ICU
Antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis
Fluconazole
 - Benefits: Low cost/tolerable
Antifungal agents ... Weaknesses: High MIC ... prolongation, alopecia ... Weaknesses: Therapeutic drug ... Coccidioidomycosis #pharmacology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... Other triggering events ... the underlying pathophysiology ... intensive care unit (ICU
Overview of antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis.
Fluconazole - Low
of antifungal agents ... tolerable • High MIC ... prolongation, alopecia ... • Therapeutic drug ... comparison #table #pharmacology