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differential management criticalcare delirium dermatology pharmacology agitation algorithm anticonvulsants ck comatose complications creatine diffuse elevated focal hair hemophagocytic hlh kinase
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
) Differential Diagnosis ... • Hyperthyroid drugs ... Disease • Discoid ... Diffuse #Focal #HairLoss ... #Algorithm #causes
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Diagnosis Framework ... Skin Disease: Discoid ... Scaling, pustules, crusts ... #Differential #Diagnosis ... #dermatology #Hairloss
Pain, Agitation, and Delirium (PAD) in the ICU Addressing the ICU Triad (PAD) can be accomplished through
Delirium (PAD) in the ICU ... Addressing the ICU ... assessment of the ICU ... A dissociative drug ... #CriticalCare #diagnosis
Delirium in the ICU Defining delirium Types of delirium Consequences of delirium Reversible causes of delirium Drug-induced delirium Non-pharmacologic management of delirium Pharmacologic
Delirium in the ICU ... delirium Reversible causes ... of delirium Drug-induced ... theABofPharmaC #ICU ... #criticalcare #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
areas -> Scaring alopecia ... hair follicles -> causes ... butterfly) Rash • ICx ... Manifestations #pathophysiology ... #diagnosis #signs
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
cytotoxic reaction to drug ... pruritus, weight gain ... , alopecia (unusual ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Creatine Kinase - Causes ... CK Elevation (Pain ... RHABDOMYOLYSIS - Drugs ... Illness Myopathy (ICU ... #differential #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Auto-amplification loop Diagnosis ... immune deficiency, Drugs ... , Unknown cause ... of emergency, ICU
The Neurological Evaluation of a Comatose Patient Definition: • Coma: a state of unresponsiveness; the absence of
Differential Diagnosis ... • Mutism Pathophysiology ... Possible responses to pain ... • If ok with ICU ... Casey Albin MD @
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