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pharmacology overview antibiogram coverage diagnosis management review sensitivities table antibiotic chloramphenicol classes classification criticalcare differential failure hemophagocytic hlh icu lymphohistiocytosis
ANTIBIOTIC SUSCEPTIBILITIES IN INTENSIVE CARE Antibiotic spectra made simple(r). Version 2, now updated with new bugs &
with new bugs & drugs ... #Classes #Bacterial ... #Spectra #Spectrum ... Susceptibilities #ICU ... CriticalCare #Overview #Pharmacology
Antibiotic classification refers to the categorization of antibiotics based on their chemical structure, mechanism of action,
of action, and spectrum ... the growth of bacteria ... synthesizing proteins in bacteria ... pathways that bacteria ... #Antibiotics #pharmacology
For my UME micro course, I made a figure that captures this terminology and lets learners
clinically important bacteria ... contrast important drug ... classes with granularity ... common beta lactam drugs ... #antibiogram #pharmacology
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Causes of Antibiotic ... Bug: Atypical bacteria ... Immunocompromise Treatment ... Spectrum (MRSA/ ... • Secondary to Treatment
Sulfonamides - Antibiotics Class Overview BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic Spectrum: Wide
: Wide spectrum ... including typical bacterial ... including PCP PNA (drug ... choice, both for treatment ... #Pharmacology #Antibiotics
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
.), Bacteria (Mycobacteria ... immune deficiency, Drugs ... Treatment: • Etiological ... of emergency, ICU ... diagnosis #management #treatment
Chloramphenicol - Antibiotics Class Overview – 50S ribosomal inhibitor. IV or PO (but PO form
Spectrum: Broad ... spectrum vs Gram ... Chloramphenicol +/- Bactrim ... several weeks after drug ... #Pharmacology #Antibiotics
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