11 results
ANTIBIOTIC SUSCEPTIBILITIES IN INTENSIVE CARE

Antibiotic spectra made simple(r). Version 2, now updated with new bugs &
ANTIBIOTIC SUSCEPTIBILITIES ... with new bugs & drugs ... Susceptibilities #ICU ... CriticalCare #Overview ... #Pharmacology #
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
Class Overview ... gram positive agent ... Drug of choice for ... #Pharmacology #Antibiotics ... #Review #Overview
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Class Overview ... synthase à fungicidal agent ... vs Candida -> Drug ... But higher MICs ... Anidulafungin #Pharmacology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia - Overview ... - Cytotoxic drugs ... - β-lactam antibiotics ... salts • Chemical Agents ... Benzene • Physical Agents
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
- Infectious Agents ... Group A Strep - Drugs ... - I.e., antibiotics ... nephrotic/nephritic syndrome ... HenochScholeinPurpura #Pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
(PRES) Overview ... Immunosuppressive agents ... Etiology: • Pathophysiology ... abnormality, Medication/Drug ... titratable parenteral agents
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Propofol infusion syndrome ... A dissociative drug ... non-OTC prolonging agent ... No pharmacologic ... (Haldol) - No pharmacologic
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
Sulfonamides - Antibiotics ... Class Overview ... apart from other agents ... including PCP PNA (drug ... #Pharmacology #Antibiotics
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
Serotonin Syndrome ... Findings Serotonin Syndrome ... antidepressants, antibiotics ... , drugs of abuse ... #Pathophysiology
Chloramphenicol - Antibiotics Class Overview

– 50S ribosomal inhibitor.   IV or PO (but PO form
Chloramphenicol - Antibiotics ... Class Overview ... several weeks after drug ... Gray baby syndrome ... #Pharmacology #Antibiotics