13 results
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
Kidney Injury • Drug ... 24-72 hours of drug ... • Treatment includes ... #Vancomycin #AKI ... #pharmacology #
IDSA - Clinical Strategy to Build an Individualized Treatment Regimen for Multi-Drug Resistant Tuberculosis (MDR-TB)
 •
Individualized Treatment ... are contacts of infectious ... over injectable agents ... MDRTB #management #Treatment ... antimicrobials #regimens #pharmacology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... immune deficiency, Drugs ... Unknown cause Treatment ... of emergency, ICU ... diagnosis #management #treatment
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
synthase à fungicidal agent ... vs Candida -> Drug ... severe Candida infections ... But higher MICs ... Anidulafungin #Pharmacology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Drugs (Statins), ... ETOH Infection ... Dermatomyositis) AKI ... - Pathophysiology ... oxidative iniury Treatment
Hepatorenal Syndrome - Diagnosis and Management Summary
Who gets HRS?
 • Decompensated cirrhosis
 • Typically with existing
Management Summary Who gets ... abuse, Bacterial infection ... Mainstay of treatment ... in HRS-AKI is vasoactive ... Typically requires ICU
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Immunosuppressive agents ... Etiology: • Pathophysiology ... Diagnosis: • Infection ... abnormality, Medication/Drug ... epilepticus Treatment
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
to a preceding infection ... Other triggering events ... the underlying pathophysiology ... and cauda equina TREATMENT ... intensive care unit (ICU
IDSA Recommendations for Preventing and Treating Disseminated Mycobacterium Avium Complex in HIV-AIDS
Preventing 1st Episode of Disseminated
necessary based on drug-drug ... used with ARV drugs ... IDSA #Prevention #Treatment ... opportunistic #infections ... #HIVAIDS #pharmacology
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
apart from other agents ... including PCP PNA (drug ... choice, both for treatment ... patients, Salmonella infections ... #Pharmacology #Antibiotics