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pharmacology management antifungal coccidioides coccidioidomycosis overview review anidulafungin antifungals bactrim bloodbrain caspofungin classification cns comparison csf diffusion dosing echinocandins idsa
Antibiotics and CNS Diffusion 1. Drugs with good CNS diffusion: - Fluoroquinolones, Fluconazole, voriconazole, Rifampin, Oxazolidinones, Metronidazole 2. Drugs
Antibiotics and ... : - β-lactam agents ... Macrolides #Antibiotics ... Perfusion #CSF #Pharmacology ... #Penetration #Antimicrobials
IDSA - Clinical Strategy to Build an Individualized Treatment Regimen for Multi-Drug Resistant Tuberculosis (MDR-TB) •
Individualized Treatment ... over injectable agents ... MDRTB #management #Treatment ... #antimicrobials ... #regimens #pharmacology
Antifungal Echinocandins - Antibiotics Class Overview Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Echinocandins - Antibiotics ... synthase à fungicidal agent ... vs Candida -> Drug ... But higher MICs ... Anidulafungin #Pharmacology
Sulfonamides - Antibiotics Class Overview BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic Spectrum: Wide
Sulfonamides - Antibiotics ... apart from other agents ... including PCP PNA (drug ... choice, both for treatment ... #Pharmacology #Antibiotics
Antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis Fluconazole - Benefits: Low cost/tolerable
Antifungal agents ... effects in the treatment ... Weaknesses: High MIC ... Weaknesses: Therapeutic drug ... Coccidioidomycosis #pharmacology
Overview of antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis. Fluconazole - Low
of antifungal agents ... effects in the treatment ... tolerable • High MIC ... • Therapeutic drug ... comparison #table #pharmacology
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