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management diagnosis pharmacology coccidioides coccidioidomycosis medications antifungal antifungals comparison druginduced encephalopathy erythematosus hemophagocytic hlh lupus lymphohistiocytosis neurology posterior pres reversible
Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): •
Drug Induced Systemic ... for 1 year of treatment ... #pharmacology # ... risk #differential ... #diagnosis #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... immune deficiency, Drugs ... Unknown cause Treatment ... of emergency, ICU ... #summary #rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Immunosuppressive agents ... Etiology: • Pathophysiology ... Reversible course Differential ... abnormality, Medication/Drug ... epilepticus Treatment
Antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis Fluconazole - Benefits: Low cost/tolerable
Antifungal agents ... effects in the treatment ... Weaknesses: High MIC ... Weaknesses: Therapeutic drug ... Coccidioidomycosis #pharmacology
Overview of antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis. Fluconazole - Low
of antifungal agents ... effects in the treatment ... tolerable • High MIC ... • Therapeutic drug ... comparison #table #pharmacology
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