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diagnosis treatment hematology aecopd aflp amiodarone apml ards cheatsheet copd criticalcare differential differentiation exacerbation fatty hepatopulmonary induced leukostasis liver lysis
Acute Respiratory Distress Syndrome – ARDS: Clinical Cheat Sheet An acute diffuse, inflammatory lung injury, leading to
Distress Syndrome ... leading to increased pulmonary ... detected on CT or CXR ... there is no clear cause ... the underlying cause
Algorithm for Management of Acute Exacerbation of COPD (AECOPD) Obtain workup for alternate diagnoses and relevant comorbidities:
Algorithm for Management ... of Acute Exacerbation ... ventilated • CXR ... , Lung US, Echo, ... #treatment #pulmonary
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... granulomas within the lungs ... e.g. incidental CXR ... Pulmonary: dyspnea ... sarcoidosis Pulmonary
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... , dyspnea, +/- CXR ... - ACS, AKI, acute ... TLS #diagnosis #management ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... common • Imaging: CXR ... - pulmonary opacities ... Diagnosis: >3 symptoms ... APML #diagnosis #management
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... postpartum): • Initial symptoms ... AP, ↑INR, ↑BUN/Cr ... ↓Antithrombin Ill ... Liver #Pregnancy #hepatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis), MPA ... or serologies + symptoms ... Goodpasture's cause ... sparing of the lung ... differential #diagnosis #management
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... disease Caused ... defect (Type 1) or anatomic ... resolution of symptoms ... #treatment #hepatology
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
toxicity (e.g., acute ... respiratory distress syndrome ... Exclude other causes ... Exclusion of other ILDs ... #diagnosis #management
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