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diagnosis management treatment aspergillus betadglucan infectiousdiseases abscess bcnie bee biomarkers bloodculture cardiology cardiomyopathy causes comparison endocarditis falsepositives humoral ia immunity
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
and Aspergillus Galactomannan ... cut-offs defined in clinical ... formulations (e.g ... beta-glucans (e.g ... BAL GM does not differentiate
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
component of many fungi ... cut-offs defined in clinical ... formulations (eg ... >90% (In most clinical ... in BAL does not differentiate
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
immunosuppression (eg ... HIV/AIDS, CGD) Clinical ... • Aspergillus Galactomannan ... Management #treatment #fungal
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Clinical ... Prevotella • Fungal ... Lung Abscess Differential ... • Vasculitis (e.g ... Abscess #pulmonary #differential
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... cardiomyopathy (e.g ... hemodynamics (e.g ... LVEF recovery (e.g ... teratogenic GDMT meds (e.g
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
skull neoplasms (e.g ... MRI lesions and clinical ... consistent with MS ... noninflammatory #differential
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
fastidious bacteria or fungi ... antimicrobials, clinical ... Tropheryma whipplei, Fungi ... special stains (e.g ... Endocarditis #diagnosis #differential
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Pathogenesis and Clinical ... bacteria, viruses, fungi ... storage sites (e.g ... proliferate and differentiate
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