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diagnosis disease management agglutinin anemia approach arthritis behcet classification gout hemolysis hemolytic joint pain signs symptoms treatment vasculitides vasculitis workup
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Autoimmune: Warm AIHA, Cold ... Drug-associated, PCH, Evans Syndrome ... Laboratory Tests ... #Diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... younger pts) Differential ... • Diagnostic Test ... Donath-Landsteiner test ... hemolytic #anemia #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
matter, spinal cord ... is a skin prick test ... Behcet disease) Differential ... Giant retinal tears ... signs #symptoms #rheumatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
present both at rest ... e.g., meniscal tears ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... • Cogan Syndrome ... well as inner ear ... retinopathy Lab Tests ... #diagnosis #rheumatology
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
sex • Metabolic syndrome ... not possible • Ultrasound ... Dual-energy CT → MSU ... 2 attacks in a year ... management #treatment #rheumatology
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