8 results
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... cauda equina ... #management #treatment ... #neurology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
Cauda Equina Syndrome ... • Transverse myelitis ... cord • Guillain-Barre ... • Provocative Tests ... diagnosis #causes #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... sensitive tests ... the underlying pathophysiology ... cauda equina TREATMENT ... #management #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... negative, MOG-IgG test ... , Hep A/B/CMV, TB ... #diagnosis #management ... #neurology #differential
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Bedside: ice pack test ... /Edrophonium test ... immunologic assay - MuSK ... Gravis #diagnosis #management ... #neurology
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
include a: • Neurologic ... II ○ Susac’s syndrome ... Noise trauma ○ MS ... Labyrinthitis ○ Epstein-Barr ... zoster virus ○ HIV
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neuritis • Partial myelitis ... • Or brainstem syndromes ... - Oligoclonal bands ... sclerosis #diagnosis #management ... #neurology #treatment
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... system: small-fiber ... neuropathy, transverse myelitis ... phenomenon (16%) MSK ... Rheumatology #Diagnosis #Management