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Workup for Vitamin B12 and Folate Deficiency #Workup #VitaminB12 #Folate #Deficiency #FolicAcid #Diagnosis #Macrocytosis #MacrocyticAnemia #Algorithm
Vitamin B12 and Folate ... Workup #VitaminB12 #Folate ... FolicAcid #Diagnosis #Macrocytosis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Neutrophils - Low RBC Folate ... Myelodysplastic Syndromes Macrocytosis ... Rule out B12 and Folate ... Macrocytic #Anemia #Macrocytosis
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
patients with macrocytosis ... but undiagnosed, folate ... #Diagnosis #Macrocytosis ... Anemia #VitaminB12 #Folate
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
If persistent macrocytosis ... • Supplement folate
Folic acid is a synthetic member of the folate (Vitamin B9) family, a group of chemically
member of the folate ... Naturally occurring folates ... Dietary folates ... Overview #Review #Folate
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
Etiologies of Folate ... increased needs for folate ... underlying mild folate ... consumption of folate ... In addition, folate
Methylmalonic Acid and Homocysteine Levels in Vitamin B12 and Folate Deficiency • B12 Deficiency: MMA elevated,
Vitamin B12 and Folate ... Homocysteine elevated • Folate ... Homocysteine #B12 #MMA #folate
Diagnosing Vitamin B12 and/or Folate Deficiency It turns out that simply measuring serum levels of B12 or
Vitamin B12 and/or Folate ... levels of B12 or folate ... Serum folate levels ... Since folate is ... #VitaminB12 #Folate
Thalassemia - Electrophoresis - Comparison Table In this disorder it is the defective production of hemoglobin that
that leads to microcytosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Deficiency • Folate ... Deficiency • Folate
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