12 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... reticularis Differential ... Polyangiitis #GPA #dermatology ... #rash #diagnosis ... #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
kidney failure DDX ... with leukopenia, anemia ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... and thymoma DDX ... result from low blood ... #oncology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... weeks without infection ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Causes: - Idiopathic ... DDX: - Pyoderma ... neutrophils in the blood ... #dermatology #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out ... Myeloproliferative Disease ... count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... - infiltrates (anemia ... plaques) AML Dx ... #Leukemia #Hematology ... #Oncology #Diagnosis
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
/sx urticaria, maculopapular ... rash, pruritis, ... Infection - Infection ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
S/sx: Fever, flank ... /sx urticaria, maculopapular ... rash, pruritis, ... #Transfusions #diagnosis ... #management #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
pulses, bruits, or blood ... , mucositis • Rash ... tract, and often causes ... vesicles, pustules, maculopapular ... #Diagnosis #Rheumatology