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leukemia syndrome vasculitis chronic classification dermatologic erythematosus granulomatosis joint lymphocytic macrophage management mas monoclonal pain paraproteinemias polyangiitis rashes sweet vasculitides
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
• Rheumatic fever ... Sarcoidosis • GPA ... Sarcoidosis #dermatology ... #rashes #differential ... #diagnosis #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... lesions (9.4%) • Maculopapular ... reticularis Differential ... #dermatology #rash ... #diagnosis #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
SLL CLL Epidemiology ... weeks without infection ... Hepatomegaly • Skin ... #workup #oncology ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... fibromyalgia) • Infections ... activation and/ ... #Systemic #Lupus ... #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... (SLL) CLL Symptoms ... -> Invade Skin: ... #Hematology #Oncology ... #Diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... [SLE], AOSD) • ... Infection (eg, ... #Management #Hematology ... #Rheumatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... (malignancy), lymphoma ... DDX: - Pyoderma ... ’s syndrome - Lupus ... #dermatology #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... Diagnosis: Systemic ... to exclude are infections ... vasculitis, and SLE ... #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(HCV) • CLL & ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis: • Systemic ... , such as SLE, atherosclerotic ... , mucositis • Rash ... vesicles, pustules, maculopapular ... #Diagnosis #Rheumatology
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