9 results
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... salmon-colored maculopapular ... rash, arthritis ... : high fever, CRP ... #AOSD #rheumatology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
nonpruritic macular or maculopapular ... Leukocytosis (10,000/microL ... Leukocytosis (10,000/microL ... #AOSD #diagnosis ... #rheumatology #
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
extensive skin rash ... • Maculopapular ... Fever >38.5 2. ... Resolution > 15 days Differentials ... withdrawal • Mild disease
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... /sx urticaria, maculopapular ... rash, pruritis, ... Infection - Infection ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
S/sx: Fever, flank ... /sx urticaria, maculopapular ... rash, pruritis, ... • Infection - ... diagnosis #management #hematology
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand
70 M vertebral osteomyelitis on vancomycin and cefepime for
diffuse palpable rash ... Differential for ... includes drug reaction ... Hand #skinrash #dermatology ... #clinical #photo
Symmetrical Drug-Related Intertriginous and Flexural Exanthema (SDRIFE)

49M +burning rash groins/buttocks (pic in next thread) x 1d.
No fever. 120/80 ... for a recent ear infection ... SDRIFE is a drug reaction ... Washington University ID ... #clinical #photo
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... , drug reactions ... , mucositis • Rash ... vesicles, pustules, maculopapular ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Coronary arteries - Fever ... mucositis - Rash ... , drug reactions ... to exclude are infections ... Vasculitis: • Fevers