21 results
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... , HBV, HCV, HEV, ... , PBC, PSC, Cystic ... hepatitis: < 1 • Cirrhosis ... #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... Elevated ALP 2. ... #PBC #Primary ... #Biliary #Cirrhosis ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Ducts - PBC ... Congenital, Others, Cirrhosis ... - CBD stone, Biliary ... #diagnosis #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
biliary obstruction ... • Obstructive: Malignancy ... , 1° PBC, 1° PSC ... Extrahepatic • Biliary ... #algorithm #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... Cholestatic: Benign/malignant ... , Primary biliary ... dechallenge • Acute ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... Cirrhosis (PBC) ... - gallstone or malignancy ... #Primary #Biliary ... #Cirrhosis #PBC
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Leukocytes • Malignancy ... - Drugs - Primary ... (PBC) - Other ... - Other biliary ... #hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Presence of CP or PC ... severe liver injury ... liver failure ... #Indications #management ... #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Algorithm • ... viremia or have cirrhosis ... • Monitor: CBC ... HAV immunity; Liver ... #Hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
hepatitis serologies, HCV ... Mixed - Check Acute ... hepatitis serologies, HCV ... hepatitis: < 1 • Cirrhosis ... #differential #Hepatology