22 results
Guillain-Barre Syndrome
An acute polyneuropathy (disorder Of the peripheral nervous System).
Symptoms are Often symmetrical and progress Over
Guillain-Barre Syndrome ... disorder Of the peripheral ... GuillainBarre #Syndrome ... #Diagnosis #Neurology
Algorithm showing a stepwise approach to the assessment and investigation of a possible neuropathy. CIDP, chronic
CIDP, chronic inflammatory ... GBS, Guillain-Barré ... syndrome; HNPP, ... #Diagnosis #Neurology ... #Neuropathy #Peripheral
Multi-System Inflammatory Syndrome in Children (MIS-C) vs. Kawasaki Disease
CDC Case Definition for MIS-C;
 • < 21
Multi-System Inflammatory ... Syndrome in Children ... disease • Positive COVID ... MISC #Kawasaki #Comparison ... #Syndrome #Children
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Etiologies of Peripheral ... disease, Leprosy • Inflammatory ... CIDP, Guillain-Barre ... Paraprotein-associated (POEMS syndrome ... diagnosis #causes #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... like illnesses, COVID ... #Syndrome #diagnosis ... #management #treatment ... #neurology
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Idiopathic Inflammatory ... Antisynthetase Syndrome ... TerrierBen #Inflammatory ... Idiopathic #Myopathy #Comparison ... #Managment #algorithm
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... cross-reacts with peripheral ... or the axon of peripheral ... #Syndrome #diagnosis ... #management #neurology
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
Neuroleptic malignant syndrome ... ; Serotonin syndrome ... as they lead to peripheral ... #Hyperthermia #comparison ... #diagnosis #management
Summary of Infections in which Steroids play a role in treatment
 • TB meningitis
 • TB
pneumonia • COVID ... reconstitution inflammatory ... syndrome (IRIS) ... • Ramsay Hunt syndrome ... Indications #infections #management
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
• Acute stroke syndromes ... Lesions Of The Peripheral ... Paraneoplastic syndrome ... • Inflammatory ... Differential #Diagnosis #neurology