20 results
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19

IL-6 activates T cells and macrophages, among other cell types (see
Siltuximab) in COVID19 ... Cytokine Activation Syndrome ... correlate with severe COVID ... #Pharmacology # ... Management #Medications
In 2018, opioid withdrawal should be considered a buprenorphine deficiency. Otherwise, a multitude of comparatively ineffective
comparatively ineffective treatments ... in high enough doses ... @emupdates #Management ... #Pharmacology # ... Pain #NonOpioid
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Propofol infusion syndrome ... glycol (solvent) toxicity ... No pharmacologic ... (Haldol) - No pharmacologic ... CriticalCare #diagnosis #management
Pearls for Treatment of Alcohol Use Disorder

First-line pharmacotherapies for moderate to severe AUD include naltrexone and
Pearls for Treatment ... include abdominal pain ... respectively) at the doses ... #UseDisorder #Management ... #Medications #Pharmacology
ED Opioid Stewardship Algorithm

Opioid Naive vs Opioid Tolerant

1. Patient Specific, Pain Syndrome-Targeted Approach
2. Combinations of Non-Pharmacologic
Syndrome-Targeted ... Combinations of Non-Pharmacologic ... Medication Assisted Treatment ... Stewardship #Algorithm #Management ... #Pain #ED
Neurological Side Effects of Antipsychotic Drugs
Acute dystonia - Spasm of muscles of tongue, face, neck, back
• Tx: Reduce dose ... greatest risk • Tx: Dose ... tremor ("rabbit syndrome ... #SideEffects #pharmacology ... #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
like illnesses, COVID ... Hands or feet • Pain ... Treatment: • Plasmapheresis ... #diagnosis #management ... #treatment #neurology
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
this maneuver does ... - Intense pain ... days, the local pain ... including DM • Treatment ... #treatment
Hydroxychloroquine is an antimalarial & DMARD (disease modifying antirheumatic drug). It is currently being discussed as
prophylaxis and treatment ... for COVID-19, although ... vomiting; abdominal pain ... COVID-19 NOTE: be ... Hydroxychloroquine #HCQ #Pharmacology
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
of patients • Dose ... starting amiodarone treatment ... respiratory distress syndrome ... Pleuritic chest pain ... Pulmonary #diagnosis #management