49 results
Hydroxychloroquine and Chloroquine in COVID19

Dosing:
Hydroxychloroquine:
 - 400mg PO BID on the first day, followed by 200mg
Chloroquine in COVID19 ... agent (increased toxicity ... #Chloroquine #COVID19 ... #HCQ #Pharmacology ... #Management #Medications
This is an oversimplified, hypothetical model to think about time from symptom onset and stages of
about time from symptom ... of disease in COVID ... #COVID19 #COVID ... infectiousdisease #clinical ... #management #treatment
Antidepressant Medications Decision Aid
 - The choice of depression medications in primary care is difficult as
across agents' toxicity ... #Management #PatientInfo ... #PrimaryCare #Psychiatry ... SNRIs #Selection #Pharmacology
Gamma hydroxybutyrate (GHB) - Toxicology

Clinical presentation
 - Symptoms of GHB toxicity include: short term anterograde amnesia,
Toxicology Clinical ... of GHB toxicity ... GHB #Toxicology #Toxicity ... #Diagnosis #Management ... #Pharmacology
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19

IL-6 activates T cells and macrophages, among other cell types (see
Siltuximab) in COVID19 ... Cytokine Activation Syndrome ... correlate with severe COVID ... #Pharmacology # ... Management #Medications
Pediatric Inflammatory Multisystem Syndrome Temporally associated with SARS-CoV-2 infection (PIMS-TS)
Clinical features
all: fever > 101.3 F
most: oxygen
Inflammatory Multisystem Syndrome ... infection (PIMS-TS) Clinical ... #Inflammatory #Syndrome ... #PIMSTS #covid19 ... diagnosis #Signs #Symptoms
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Induced Muscle Toxicity ... - Summary Clinical ... IU/I • SAMS clinical ... Statin #muscle #toxicity ... myopathy #diagnosis #management
Drugs Used for the Treatment of COVID-19 Infection

** Editor Note (from ophthalmology MD input) - Hydroxychloroquine/chloroquine
the Treatment of COVID ... highlighted circle= clinical ... Medications #Treatment #COVID19 ... #Pharmacology # ... Table #Management
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
presentation - Clinical ... also includes symptoms ... LacticAcidosis #Toxicity ... Toxicology #Diagnosis #Management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
brain PRES Clinical ... PRES-Associated Clinical ... Neurological symptoms ... Medication/Drug toxicity ... #diagnosis #management