14 results
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Diagnosis Algorithm ... Primary Causes ... renal failure/uremia ... Myelodisplastic syndrome ... #causes
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Iron deficiency anemia ... discoloration) • Liver ... #Differential # ... Diagnosis #Algorithm ... #causes
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Renal Failure • Liver ... Neoplastic / Hematologic ... • Anemia • ... Malignancy Infectious ... Disease Neurologic
Causes of Pleural Effusion - Differential Diagnosis Algorithm
Transudate - Hydrostatic
 • Congestive heart failure
 • Constrictive
Causes of Pleural ... Effusion - Differential ... Diagnosis Algorithm ... Urinothorax Exudate - Infectious ... #Hepatology #causes
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Weakness • Cardio-pulmonary ... diseaseAnemia ... Lambert-Eaton Myasthenic Syndrome ... #Causes
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Liver diseases ... autoimmune hemolytic anemia ... ) • Systemic granulomatous ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Diagnosis Algorithm ... renal failure/uremia ... Myelodisplastic syndrome ... Pruritus #secondary #systemic ... #causes
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
SLE], AOSD) • Infection ... with leukopenia, anemia ... thrombocytopenia • Liver ... Treatment: • Corticosteroids ... #Diagnosis #Management
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Hematologic malignancy ... (elevations of liver ... Bone Marrow - Anemia ... #differential #
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
: • 10%-15% Pulmonary ... vasculitis: 10%-16% Liver ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... Diagnosis #Management