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diagnosis differential lfts algorithm chemistry elevation phosphatase transaminitis abnormal alkphos biliary bilirubin cholangitis cirrhosis enzymes fatty functiontest hepatitis hyophosphatasia injury
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
ALP - Biliary ... Transaminase, ALP ... / ULN ALT) / (ALP ... / ULN ALP) ... Transaminitis #diagnosis #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
(ALP) Elevation ... Diagnosis Algorithm ALP ... - Increased ALP ... #Phosphatase #ALP ... Diagnosis #Algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Cholestasis • ALP ... disease • If ALP ... • Elevation of ALP ... AST:ALT Ratios ... #differential #Hepatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
in 1923 Low ALP ... 1948 by Rathbun ALP ... synthesized in: liver ... collection with EDTA Pathophysiology ... Hyophosphatasia #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
, Alkaline Phosphatase ... Alkaline phosphatase ... Laboratory #Metabolism #ASTALT ... AlkPhos #Bilirubin #Hepatology ... #Pathophysiology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... iMedEducation #AFLP ... Pregnancy #hepatology ... diagnosis #management #pathophysiology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
specificity to elevated ALP ... • AST/ALT > ALP ... GGT/5-NT: ↑ - ALP ... be abnormal AST ... diagnosis #algorithm #hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... box indicates all ... ALP, alkaline phosphatase ... ; ALT, alanine aminotransferase ... Abnormal #Algorithm #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... PBC Labs: • Alkaline ... obstruction • ALP ... or higher • Liver ... diagnosis #workup #hepatology
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