6 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Algorithm for Transaminitis ... Wilsons, Pregnancy - AFLP ... Elevated #Abnormal #Transaminitis ... Algorithm #diagnosis #hepatology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... specific for the liver ... SinaiBmoreIMRes #Liver ... LFTs #Elevation #Transaminitis ... #diagnosis #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... iMedEducation #AFLP ... Pregnancy #hepatology ... diagnosis #management #pathophysiology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Identify Acute Liver ... - Specific to liver ... #differential #Hepatology ... #transaminitis
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
in 1923 Low ALP ... 1948 by Rathbun ALP ... synthesized in: liver ... collection with EDTA Pathophysiology ... Hyophosphatasia #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... cholestasis → Cirrhosis/Liver ... obstruction • ALP ... or higher • Liver ... diagnosis #workup #hepatology