16 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... free fatty acid metabolism ... iMedEducation #AFLP ... Liver #Pregnancy #hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... collection with EDTA Pathophysiology ... Nephrolithiasis • Metabolic ... Hyophosphatasia #hepatology ... #diagnosis
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
and Bilirubin Metabolism ... #ASTALT #AlkPhos ... #Bilirubin #Hepatology ... #Pathophysiology ... #Diagnosis #LFTs
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
NASH, Genetic / Metabolic ... By AST:ALT Ratio ... : AST:ALT = ... Liver #Injury #hepatology ... #differential #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Shock liver • Metabolic ... be abnormal AST ... #differential #diagnosis ... #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
(Alk phos/ULN ALP ... • AST/ALT > ALP ... normal AST/ALT AST ... liver #chemistry #diagnosis ... #differential #Hepatology
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
glucose, fluid, salt ... • Incr Glucose Metabolism ... Syndrome - Metabolic ... Refeeding #Syndrome #diagnosis ... #pathophysiology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome Pathophysiology ... autosomal recessive salt-losing ... → Hypokalemia Metabolic ... Gitelman #Syndrome #Pathophysiology ... #nephrology #diagnosis
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
- Differential Diagnosis ... Intake: • Low salt ... Excessive vomiting - Metabolic ... #Differential #Diagnosis ... #Algorithm #Pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... obstruction • ALP ... Differential Diagnosis ... #cholangitis #diagnosis ... #workup #hepatology