7 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... free fatty acid metabolism ... iMedEducation #AFLP ... Liver #Pregnancy #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
NASH, Genetic / Metabolic ... By AST:ALT Ratio ... : AST:ALT = ... Liver #Injury #hepatology ... #LFTs #transaminitis
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
and Bilirubin Metabolism ... #ASTALT #AlkPhos ... #Bilirubin #Hepatology ... #Pathophysiology ... #Diagnosis #LFTs
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... (Alk phos/ULN ALP ... normal AST/ALT AST ... #differential #Hepatology ... transaminitis #LFTs
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
in 1923 Low ALP ... 1948 by Rathbun ALP ... collection with EDTA Pathophysiology ... Nephrolithiasis • Metabolic ... Hyophosphatasia #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Shock liver • Metabolic ... • AST/ALT > ALP ... disease - If ALP ... be abnormal AST ... diagnosis #algorithm #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
The presence of metabolic ... ALP, alkaline phosphatase ... #LFTs #Abnormal ... #Algorithm #Hepatology