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diagnosis management rheumatology disease hemophagocytic hlh lymphohistiocytosis stills
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... hemopathies, solid cancers ... mevalonate kinase deficiency ... Prunelle Getten #AdultOnset
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... B-LNH), solid cancers ... Cellular immune deficiency ... #summary #rheumatology
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