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diagnosis management rheumatology syndrome apml arteritis classification differentiation encephalopathy gca giantcell hemophagocytic hlh hodgkins lymphohistiocytosis lymphoma mds myelitis myelodysplasia myelodysplastic
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Pathophysiology ... • Induce blast cell ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... Cellular immune deficiency ... Unknown cause Treatment
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
or folic acid deficiency ... • Copper deficiency ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Etiology: • Pathophysiology ... Reversible course Differential ... epilepticus Treatment ... underlying cause • Treatment
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... very remarkable w/differential ... of the steroid treatment ... Treatment of GCA
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Transverse Myelitis - Clinical ... • Nutritional Deficiency ... Transverse Myelitis Treatment ... #differential
Neurosarcoidosis - Diagnosis and Treatment • 5 to 40% of sarcoidosis, Heterogeneous, often inaugural • Central
Cranial nerves (ll ... neurosarcoidosis: Clinical ... , Exclusion of Differential ... #management #neurology ... #rheumatology
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