Maturation hematology photo rash skin rheumatology diagnosis management purpura erythematosus activation sle dermatology blood product symptoms pain reactions syndrome mas

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Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and

burning sensation or pain ... • Goodpasture syndrome ... Polyangiitis #GPA #dermatology ... #rash #diagnosis ... #rheumatology

Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin

Sjögrens (15%) Skin ... , Vasculitis, Purpura ... lesions Abdominal pain ... #signs #symptoms ... #diagnosis #rheumatology

Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of

Syndrome (MAS) ... rash) • Heart, ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

rash • Erythematous ... Arthritis: • Joint pain ... Induced Lupus: • Symptoms ... Chronic B-cell activation ... #Diagnosis #Rheumatology

Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient

Blood Product Transfusions ... : Fever, flank pain ... Blood products contain ... #diagnosis #management ... #hematology #reactions

Blood Transfusion Reactions

Immune Mediated:
• Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.

: Fever, flank pain ... maculopapular rash ... Blood products contain ... #diagnosis #management ... #hematology #reactions

Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
•

mucositis - Rash ... disease, drug reactions ... Presentation - Systemic Symptoms ... vasculitis, and SLE ... #rheumatology #

Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,

SLE, atherosclerotic ... disease, drug reactions ... pulses, bruits, or blood ... , mucositis • Rash ... #Rheumatology

Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear

ALL: mediastinal mass ... all phases of maturation ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis

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