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differential classification systemic algorithm causes cryoglobulinemia cryoglobulins cutaneous dermatologic granulomatosis joint macrophage mas pain petechial physicalexam polyangiitis rashes signs symptoms
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Sarcoidosis • GPA ... lesions • Discoid lupus ... #dermatology ... #differential #diagnosis ... #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Findings: • Petechiae ... Maculopapular rash ... (inflamed blood ... #dermatology #rash ... #diagnosis #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
(lupus, RA, Sjogren's ... , GPA, EGPA, Microscopic ... cryoglobulins • Skin ... #Petechiae #Rash ... Algorithm #Causes #dermatology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Secondary: CTD: SLE ... Small Vessel: Petechiae ... , Palpable purpura ... #skin #dermatology ... #rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... #erythematosus # ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
> PR3 60% • GPA ... mucositis - Rash ... erythematosus, ... , and SLE) • Urinalysis ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... rash • Erythematous ... Chronic B-cell activation ... #Diagnosis #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Skin ulcers ... - GPA, EGPA, microscopic ... (e.g. systemic lupus ... erythematosus ( ... classification #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
or purpuric rash ... SLE], AOSD) • Infection ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... pulses, bruits, or blood ... , mucositis • Rash ... MPO > PR3 60/ GPA ... #Rheumatology
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