11 results
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
SyndromeDefect ... count, Single isolated ... Syndrome (an example ... #table #differential ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #Diagnosis #hematology ... #nonpalpable #dermatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... with or without platelet ... Agglutination - Cold agglutinins ... Hemolytic #Anemia #Differential ... Algorithm #workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... . primary cold agglutin ... Extravascular #Causes #differential ... #diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin ... Syndrome (CAS): ... Viral Infection Clinical ... younger pts) Differential ... hemolytic #anemia #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
to a low blood platelet ... neutrophils and platelets ... with single-lineage ... blood count with differential ... #diagnosis #hematology
Henoch Schonlein Leg Rash - Palpable Purpura
Purpura: Low Platelets or Vasculitis?
45 years old, seen in our
Schonlein Leg Rash ... Purpura Purpura: Low Platelets ... Tip: To differentiate ... #clinical #photo ... #dermatology #HSP
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... or Qualitative defect ... in platelets == ... von Willebrand syndrome ... #Diagnosis #Hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
blood type and detects ... Washed RBC • Single ... donor (apheresis) platelets ... maculopapular rash ... diagnosis #management #hematology
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand
70 M vertebral osteomyelitis on vancomycin and cefepime for
diffuse palpable rash ... Differential for ... Churg-Strauss syndrome ... Hand #skinrash #dermatology ... #clinical #photo