12 results
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Ascites - Differential ... Diagnosis Chronic liver ... disease (cirrhosis ... Fitz-Hugh-Curtis syndrome ... Diagnosis #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... >10 mmHg - clinically ... of portal HTN: ascites ... portal HTN: • Ascites ... Diagnosis #causes #hepatology
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
- Differential ... - Hepatic: • Cirrhosis ... • Infiltrative disease ... • Acute liver ... Diagnosis #Algorithm #Hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Budd-Chiari syndrome ... Liver disease ... - Cirrhosis ... Causes #diagnosis #differential ... #hepatology #SAAG
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... develops (DIC, ascites ... infiltration) Differential ... Pregnancy #hepatology ... #obstetrics #obgyn
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... necrosis HELLP Syndrome ... of Pregnancy (AFLP ... #hepatology #obstetrics ... hepatitis #comparison #differential
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
>1.1 g/dl): - Cirrhosis ... - Massive liver ... - Acute fatty liver ... without cirrhosis ... #Diagnosis #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... vein: Budd-chiari syndrome ... hepatitis: < 1 • Cirrhosis ... • Gilbert's syndrome ... diagnosis #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
/Liver failure ... PBC Labs: • Alkaline ... obstruction • ALP ... bile ducts Differential ... diagnosis #workup #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
disease: > 2 ... hepatitis: < 1 • Cirrhosis ... • Gilbert's syndrome ... chemistry #diagnosis #differential ... #Hepatology #transaminitis