12 results
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Ascites - Differential ... Diagnosis Chronic liver ... disease (cirrhosis ... Fitz-Hugh-Curtis syndrome ... Diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Pregnancy - AFLP ... • Cholestatic disease ... • Others #LFTs ... #Hepatology #LiverEnzymes
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... disease: > 2 ... • Gilbert's syndrome ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Budd-Chiari syndrome ... Liver disease ... - Nephrotic syndrome ... Causes #diagnosis #differential ... #hepatology #SAAG
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
- Differential ... • Infiltrative disease ... • Acute liver ... #Differential # ... Diagnosis #Algorithm #Hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... develops (DIC, ascites ... infiltration) Differential ... iMedEducation #AFLP ... Pregnancy #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... necrosis HELLP Syndrome ... of Pregnancy (AFLP ... #hepatology #obstetrics ... hepatitis #comparison #differential
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... vein: Budd-chiari syndrome ... • Gilbert's syndrome ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... >10 mmHg - clinically ... of portal HTN: ascites ... portal HTN: • Ascites ... Diagnosis #causes #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Gradient (SAAG) - Differential ... - Massive liver ... Veno-occlusive disease ... - Acute fatty liver ... #Diagnosis #hepatology