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diagnosis agglutinin anemia causes cold gammopathy gap globulin hemolytic hodgkins hypertension lymphoma nonhodgkins paraproteinemias portal protein proteingap significance
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... (MGUS) - Differential ... Ig deposition disease ... Diagnosis #hematology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• MM • WM • MGUS ... • Heavy Chain disease ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... >10 mmHg - clinically ... of portal HTN: ascites ... (SAAG>I.I), esophageal ... Diagnosis #causes #hepatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
• Clinical features ... the spleen or liver ... #oncology #diagnosis ... #differential # ... hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... younger pts) Differential ... significance (MGUS ... hemolytic #anemia #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Gammopathy Include: • MGUS ... changes (POEMS syndrome ... Sarcoidosis) • Liver ... gastric tumors • Hematology ... #diagnosis #hematology
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