11 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Algorithm for Transaminitis ... Ducts - PBC ... Congenital, Others, Cirrhosis ... #Transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
, PBC, PSC, IgG4 ... stone, Malignancy, PBC ... • Bilirubin: RBC ... cardiac muscle, RBC ... • LDH: Heart, RBC
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
(PBC) - Summary ... PBC Epidemiology ... 30-65 years PBC ... PBC Signs and ... • Fatigue PBC
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
: < 1 • Cirrhosis ... • Bilirubin: RBC ... cardiac muscle, RBC ... • LDH: Heart, RBC ... #transaminitis
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... viremia or have cirrhosis ... • Monitor: CBC ... Diagnosis #Management #Treatment ... #Hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... hepatocellular pattern of liver ... reported (eg AIH-PBC ... upper limit of normal ... regarding need for treatment
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
skin infection Cirrhosis ... vulnificus part of normal ... Hippocrates in 5 BC ... sepsis: chronic liver ... can sequester iron
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... DIC • Severe Liver ... + Bleeding Treatment ... hydration • RBC ... #management #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Sarcoidosis) • Liver ... disease: Cirrhosis ... , PBC, PSC, Viral ... gastric tumors • Hematology ... chain assay • An abnormal
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
IgM) levels • Hepatitis ... Complete blood count (CBC ... profile, including liver ... ferritin level, and iron ... arthritis) • Hepatitis