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differential management bandemia coagulation dic disseminated fungal gap infections intravascular laboratory mycoses neutrophil protein proteingap rheumatic rheumatoid wbc workup
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
(RA, Temporal arteritis ... : Cirrhosis, ETOH ... autoimmune hepatitis, PBC ... gastric tumors • Hematology ... #hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Tissue damage • Leukemia ... • Autoimmune diseases ... #neutrophil #WBC ... #CBC #hematology ... #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... organ damage Clinical ... hydration • RBC ... #causes #treatment ... #management #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Complete blood count (CBC ... ferritin level, and iron ... ANA and RF (if clinical ... #testing #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... neutropenia, and iron ... Urinary antigen testing ... , neutropenia, cirrhosis ... Meningitis, septic arthritis
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