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joint msk pain antibodies antinuclear approach autoimmune basophilia biliary causes cholangitis classification gap globulin hepatology laboratory monoarthritis monoarticular myopathy myositis
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... Crohn’s Disease ... Other Causes: • Iron ... Irradiation • Cirrhosis ... #hematology #basophils
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
: The ANA patterns ... Patterns and Associated ... Primary Biliary Cirrhosis ... #patterns #rheumatology ... #diagnosis #differential
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... patients • +ANA ... bile ducts Differential ... #diagnosis #workup ... #hepatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... iron saturation ... #laboratory #workup ... #diagnosis #testing ... #Rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... • Is there a pattern ... asymmetric pattern ... #Diagnosis #MSK ... #rheumatology #
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
to Joint Pain - Diagnostic ... Joint #Pain #MSK #rheumatology ... #approach #workup ... #differential # ... diagnosis #arthritis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... Lab Tests: • CBC ... ) pattern: antibodies ... ) pattern: is usually ... #diagnosis #rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... (RA, Temporal arteritis ... : Cirrhosis, ETOH ... gastric tumors • Hematology ... #diagnosis #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... pattern of muscle ... • Nonerosive arthritis ... : • PBC, autoimmune ... Myositis #Myopathy #rheumatology
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