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rheumatology ana anemia antibodies antinuclear biliary calculation cholangitis erythematosus gap globulin hepatology hodgkins index joint laboratory lupus lymphoma management monoarthritis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... Thyroid, Autoimmune ... Primary Biliary Cirrhosis ... #rheumatology # ... diagnosis #differential
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary Cirrhosis ... Pathophysiology ... bile ducts Differential ... #diagnosis #workup ... #hepatology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
deficiencies: Iron ... Chronic kidney disease ... • Hemolysis: Autoimmune ... #anemia #differential ... #diagnosis #calculation
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... , erythema and WBC ... • Is there a pattern ... #Diagnosis #MSK ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... • Non-autoimmune ... Malignancy (e.g. hematologic ... deficiencies • Autoimmune
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... ferritin level, and iron ... (to support a diagnosis ... #laboratory #workup ... #diagnosis #testing
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Lab Tests: • CBC ... - (C-ANCA) pattern ... - (P-ANCA) pattern ... #diagnosis #rheumatology ... #classification
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... number of sites of disease ... #hematology #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... : Cirrhosis, ETOH ... , autoimmune hepatitis ... , PBC, PSC, Viral ... #diagnosis #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... slow onset and pattern ... • Nonerosive arthritis ... : • PBC, autoimmune ... #differential #
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