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algorithm bruising hemolysis intravascular mds myelodysplasia nonpalpable oncology palpable pediatrics petechiae petechial physicalexam rash rheumatology syndromes thromboticthrombocytopenicpurpura
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... purpura (TTP), ... lymphoproliferative disorders ... #Causes #differential ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... : ITP • Secondary ... /HUS - Hemolytic ... Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... Immune - ITP ... #Bruising #Causes ... #peds #pediatrics ... #diagnosis #differential
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... for Thrombotic Thrombocytopenic ... Purpura Activity ... WBC count and differential ... #Workup #Hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
in primary or secondary ... hemostasis: - Thrombocytopenia ... Vasculitis - Collagen disorders ... deficiency Work ... #Causes #dermatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Causes • Anemia ... blood count with differential ... #Syndromes #diagnosis ... #hematology #oncology
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